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Cytokine (2020) 133:155146

Molecular analyses showed that CO23RFLC had acquired a marked increased expression of the MDR1 gene encoding for an efflux pump protein mainly responsible for the drug-resistance, due to a mutation in the transcription factor gene MRR1 [16] whereas CO23RFK had a homozygous mutation (S645Y substitution) in the FSK1 gene, responsible for the synthesis of glucan [17]

99%+ purity (HPLC) Third-party tested Freedom Diagnostics Identity confirmed Certificate of Analysis Tested by Freedom Diagnostics 04/12/2026 Key Ingredients Tripeptide-copper complex studied for its ability to modulate over 4,000 human genes

Carry-over and period effects were investigated by comparing the baseline measurements at the beginning of each period (V1 and V4) as well as interpreting the beta coefficient from the interaction between the period and the assigned treatment

Involvement of thermosensitive TRP channels in energy metabolism